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A collection of short stories and poems published at the historyradio.org website, all have a dark theme. There is also a short introduction by the editor, Michael Henrik Wynn. Included in the collection are two stories by the Belgian Rosny brothers (writing under the pen name J.-H. Rosny), two gangster stories by the female pulp pioneer Margie Harris, a short story by the notorious occultist Aleister Crowley, a story by Tod Robbins, a ghost story by the Norwegian writer Rigmor Solem and a story written by the editor, Michael Henrik Wynn. There is also a poetry section with some dark poems by various authors, including Robert E. Howard and the Japanese anarchist Okamoto Jun. There are some poems by unknown writers like Angel Uriel Perales and Joshua Kwesi Knowlife.

Circadian clocks enhance the efficiency and survival of living things by organizing their behavior and body functions. There has been a long history of research seeking a link between circadian clock and tumorigenesis. Studies of animal models and human tumor samples have revealed that the dysregulation of circadian clocks is an important endogenous factor causing mammalian cancer development. The core circadian clock regulators have been implicated in the control of both the cell cycle and DNA damage responses (DDR). Conversely, several intracellular signaling cascades that play important roles in regulation of the cell cycle and the DDR also contribute to circadian clock regulation. This review describes selected regulatory aspects of circadian clocks, providing evidence of a molecular link of the circadian clocks with cellular DDR.

Circadian clocks are intrinsic time-tracking systems that endow organisms with a survival advantage. The core of the circadian clock mechanism is a cell-autonomous and self-sustained oscillator called a cellular clock, which operates via a transcription-/translation-based negative feedback loop. Under natural conditions, circadian clocks are entrained to a 24-hour day by environmental time cues, most commonly light. In mammals, circadian clocks are regulated by cellular clocks located in the central nervous system, such as the suprachiasmatic nucleus (SCN), and in other peripheral tissues. Importantly, mammals have no photoreceptors in the peripheral tissues; therefore the effect of light on peripheral clocks is indirect. By striking contrast, zebrafish peripheral cellular clocks are directly light responsive. This characteristic of the zebrafish cellular clock has contributed to the identification of molecules and signaling pathways that are involved in the light-dependent regulation of the cellular clock. Here, selected light-dependent regulatory mechanisms of circadian clocks in mammals and zebrafish are described.

The focus of the book Diagnostic Techniques and Surgical Management of Brain Tumors is on describing the established and newly-arising techniques to diagnose central nervous system tumors, with a special focus on neuroimaging, followed by a discussion on the neurosurgical guidelines and techniques to manage and treat this disease. Each chapter in the Diagnostic Techniques and Surgical Management of Brain Tumors is authored by international experts with extensive experience in the areas covered.

O principal objetivo da obra é procurar compreender como o homem de hoje vê e interpreta a realidade, para então analisar seu comportamento e seus ideais. Nesta obra, Okamoto analisa as funções e direcionamentos da arquitetura moderna, ressaltando a necessidade de resgate da convivência harmoniosa no espaço físico. O autor questiona a mera atribuição dada a esse espaço físico, de atender às necessidades básicas de trabalho, repouso, relaxamento e diversão.

"We say that we want to be happy. If that's what we really want, we should start planting seeds of happiness. The kind of flower you get depends on the seed you have planted; this is a law of nature. In the same way, if you plant the seeds of happiness, the flowers of happiness will bloom. Buddhism teaches the law of cause and effect, which enables you to become a happier you. This book applies that clear law to the troubles that various people have, explaining things in a way that will be easy for them to understand."--Amazon.com.