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This Brief explores the use of proteomics as a tool for biomarker discovery in human reproduction and summarizes current findings and trends of proteomic studies in both male and female infertility. This simplifies this important but complex topic and equips the novice reader with sufficient background information on the use of proteomics in human reproduction. The up-to-date scenario on proteomic investigations will also appeal to researchers and post graduate students looking to keep abreast with the latest developments in reproductive research. This review summarizes current findings of contemporary proteomic studies on infertility in both males and females with various reproductive pathologies, and its use in predicting the outcome of assisted reproduction. In human reproduction, the search for biomarkers via proteomics is a fast-evolving approach that involves the analysis of proteins in the reproductive tissues and fluids, such as the male gametes, seminal plasma, ovarian and endometrial tissue, and follicular and uterine fluid. By comparing the protein profile of a healthy, fertile individual against that of an infertile individual, the differentially expressed proteins may give an indication to certain proteins that could serve as useful biomarkers that are related to infertility. As proteomic studies continue to unravel the dynamic proteome behind various infertility conditions, there is potential for the discovery of prognostic markers that could ultimately help in both natural and assisted human reproduction.

This Brief explores the use of proteomics as a tool for biomarker discovery in human reproduction and summarizes current findings and trends of proteomic studies in both male and female infertility. This simplifies this important but complex topic and equips the novice reader with sufficient background information on the use of proteomics in human reproduction. The up-to-date scenario on proteomic investigations will also appeal to researchers and post graduate students looking to keep abreast with the latest developments in reproductive research. This review summarizes current findings of contemporary proteomic studies on infertility in both males and females with various reproductive pathologies, and its use in predicting the outcome of assisted reproduction. In human reproduction, the search for biomarkers via proteomics is a fast-evolving approach that involves the analysis of proteins in the reproductive tissues and fluids, such as the male gametes, seminal plasma, ovarian and endometrial tissue, and follicular and uterine fluid. By comparing the protein profile of a healthy, fertile individual against that of an infertile individual, the differentially expressed proteins may give an indication to certain proteins that could serve as useful biomarkers that are related to infertility. As proteomic studies continue to unravel the dynamic proteome behind various infertility conditions, there is potential for the discovery of prognostic markers that could ultimately help in both natural and assisted human reproduction.

vocês vão conhecer história de Samanta Antonelli 19anos, de família humilde que trabalha em um café para ajudar os pais e pagar a faculdade. Leonardo Milani um homem de 30 anos, que nunca deu nem recebeu amor, CEO de uma rede de bancos. Frio, calculista, esmaga quem cruza o seu caminho. Usa todo seu dinheiro pra comprar tudo e todos. O que vai acontecer quando a garota doce sonhadora, cruzar o caminho desse homem possessivo e dominador? será que ele vai destruir os sonhos dela ou ela vai ensiná-lo a amar?

Es la noche de Navidad y diez particulares pasajeros esperan el vuelo 727, en la sala de embarque número 33 del Aeropuerto Internacional. Sus vidas, aparentemente distantes y muy diferentes, se verán enlazadas cuando Samanta, la Tormenta del Siglo, avance hacia ellos decidida a destruirlo todo. A medida que transcurren los minutos, la borrasca empeora y la lluvia arremete cada vez con mayor furia. Pareciera que los diez pasajeros están condenados a morir. ¿Habrá alguna esperanza para ellos?, ¿podrán superar sus diferencias y así encontrar una forma de salvarse? Un famoso mago y una bebé serán la clave para sobrevivir.

La pandemia por coronavirus significó un parteaguas en la relación entre la educación y el universo digital. Sin embargo, distintas experiencias educativas a través de medios digitales —que sin dudas se vieron potenciadas por la pandemia— ya venían asomando desde hacía tiempo. Este es el caso de los edutubers, que son docentes que publican videos explicativos en YouTube sobre las más diversas temáticas. Para estudiar el fenómeno, los expertos en Comunicación, Educación y Medios Digitales Francisco Albarello, Francisco Arri y Ana Laura García Luna charlaron en profundidad con ocho edutubers argentinos. A partir de estas conversaciones —y de su articulación con un importante y actualizado corpus teórico—, los autores logran dar cuenta de una modalidad de enseñanza y aprendizaje que recupera prácticas tradicionales y se transmite por nuevos canales. Como si fuese una continuidad de su último libro sobre booktubers, Edutubers: docentes en pantallas es tanto una introducción al fenómeno como una nueva oportunidad para pensar qué es la educación llegando al primer cuarto del siglo XXI.

Una mujer huye de un grupo de policías que la persiguen sin descanso. Está a punto de perderlos de vista cuando el auto en el que viaja se detiene a mitad de la carretera y su única escapatoria es bajar el pesado camino y correr directo al desierto que se extiende bajo sus pies. Ella está a punto de morir por el cansancio que la invade cuando algo extraño ocurre; es transportada a otro lugar, uno donde algo aterrador la espera. Un relato, una historia de origen que te hará entender los favores que se le pedirán y que deberá realizar con los ojos cerrados.

Recuperando el título de un pequeño cuento con el que la puertorriqueña Rosario Ferré analizó la misoginia literaria en los años 90, este 'El coloquio de las perras' pretende ser un homenaje a las escritoras hispanohablantes que sortearon todo tipo de obstáculos para hacer su literatura. Desde populares figuras como Elena Garro, Gabriela Mistral o Alejandra Pizarnik hasta otras más desconocidas como Alcira Soust Scaffo, Agustina González López o María Emilia Cornejo, la periodista y poeta Luna Miguel entabla una conversación llena de ladridos con una docena de mujeres, con la voluntad de que sus obras sean leídas y reivindicadas, y tal vez con la esperanza de que la egoísta y peligrosa raza del "escritor macho" quede de una vez por todas extinguida.

A rich analysis of the complex dynamic between food collection and food production in the farming societies of precolonial south central Africa Engaging new linguistic evidence and reinterpreting published archaeological evidence, this sweeping study explores the place of bushcraft and agriculture in the precolonial history of south central Africa across nearly three millennia. Contrary to popular conceptions that place farming at the heart of political and social change, political innovation in precolonial African farming societies was actually contingent on developments in hunting, fishing, and foraging, as de Luna reveals.

The first social history examining all aspects of Brazil's radical transition from a predominantly rural society to an urban one.

The editorial project, presented in two volumes, by Emilio Bustamante y Jaime Luna Victoria, film critics, screenwriters, and academics, offers an approach to film production in the different regions of Peru, with the exception of the metropolitan area of Lima and Callao. Volume 1 comprises melodramas in which the fears and aspirations of migrants of rural origin are expressed, horror films of monsters from the Andean oral tradition like jarjachas, pishtacos and the condemned, or Amazon mythology as the Tunche or Chullachaqu; documentaries, experimental short films and feature films. In the second volume, 32 Peruvian filmmakers representing their respective regions share their production methods, preparation, distribution and exhibition of their films and explain their artistic and professional challenges and expectations.