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The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Using examples from real clinical trials, Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority tr

This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1972.

This book discusses the issues surrounding race, ethnicity, and immigrant status in U.S. policing, with a special focus on immigrant groups’ perceptions of the police and factors that shape their attitudes toward the police. It focuses on the perceptions of three rapidly growing yet understudied ethnic groups – Hispanic/Latino, Chinese, and Arab Americans. Discussion of their perceptions of and experience with the police revolves around several central themes, including theoretical frameworks, historical developments, contemporary perceptions, and emerging challenges. This book appeals to those interested in or researching policing, race relations, and immigration in society, and to domestic and foreign government officials who carry law enforcement responsibilities and deal with citizens and immigrants in particular.

Practical Peripheral Vascular Intervention, Second Edition is a how-to guide to state-of-the-art vascular interventional procedures for all arteries and veins outside the coronary vascular system. Chapters on each artery cover indications for interventional procedures, vascular anatomy, access, diagnostic angiography, and specific interventional techniques used by experienced practitioners. This thoroughly updated edition includes an expanded section on intracranial stenting, additional material on venous filters, venous thrombosis, and central venous occlusion, and more chapters reviewing all cardiac noninvasive modalities. More than 300 large-size illustrations show trainees and clinicians the best approach to treatment.

History of the Book The last three decades have witnessed an explosive development in - tegrated circuit fabrication technologies. The complexities of current CMOS circuits are reaching beyond the 65 nanometer feature size and multi-hundred million transistors per integrated circuit. To fully exploit this technological potential, circuit designers use sophisticated Computer-Aided Design (CAD) tools. While supporting the talents of innumerable microelectronics engineers, these CAD tools have become the enabling factor responsible for the succe- ful design and implementation of thousands of high performance, large scale integrated circuits. This book (a research monograph) originated from a body of doctoral d- sertationresearchcompletedbythe?rstauthorattheUniversityofRochester from 1994 to 1999 while under the supervision of Prof. Eby G. Friedman. This research focuses on issues in the design of the clock distribution network in large scale, high performance digital synchronous circuits and particularly, on algorithmsfornon-zero clockskewscheduling.Duringthedevelopmentofthis research, it became clear that incorporating timing issues into the successful integrated circuit design process is of fundamental importance, particularly in that advanced theoretical developments in this area have been slow to reach the designers’ desktops. The second edition of the book is enhanced by the body of doctoral dissertation research completed by the second author at the University of Pittsburgh from 2000 to 2005 under the supervision of Prof.

In this chapter we propose a method for the extraction of data from network flow and a contextual separation of partial connections, using a set of network metrics that create a signature defining the connection behavior. We begin with defining the input dataset of captured communication and the process of extracting metrics from separated connections. Then we define the set of metrics included in the final behavioral signature. The second part of the chapter describes experiments performed with a state-of-the-art set of network metrics, with comparison to our proposed experimental set. The chapter concludes with the results of our experiments.

This publication covers a wide variety of aspects in pump irrigation, ground water, water wells, and costs involved in the use of ground water for irrigation.