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Single-trial analyses of EEG signals have demonstrated a relationship between the instantaneous phase and cortical excitability (Bergmann et al., 2012; Massimini et al., 2003; Thies et al., 2018), sensory thresholding (Ai & Ro, 2014), and intracranial electrical activity (Haegens et al., 2011; Miller et al., 2012). Considering the relationships associated with EEG phase, accurately predicting phase in real-time has multiple benefits. The ability to accurately target phase will give researchers greater power in future phase-behavior experiments, potentially revealing how phasic processes are implemented and maintained in neuronal populations. Accurate phase prediction can help neuromodulation techniques in a closed-loop fashion, particularly non-invasive brain stimulation (Zrenner et al., 2018), which may operate through phase-resetting mechanisms (Kawasaki et al., 2014). Brain-computer interfaces implementing phase measures (Brunner et al., 2006; Hsu, 2015) will also benefit from increased real-time phase estimation.The current cognitive faculty (e.g., attention) an individual is engaged in affects ongoing oscillations (Klimesch, 1999). These changes are manifested through altered signal-to-noise ratios in the oscillations (Pijn et al., 1991). Although there are many ways to characterize an individual's cognitive state, a basic distinction can be made between rest (eyes-open and eyes-closed) and task states. Neuroimaging shows differences among these states, with default mode network activation in resting-state functional connectivity studies, and alpha-band power increase during rest (Raichle, 2015; Compston, 2010). Although these states exhibit large changes in neuroimaging, how they affect EEG phase prediction accuracy is currently unknown. The current project compared EEG phase prediction accuracy in the occipital alpha band between rest and task. Parieto-occipital alpha waves are an ideal signal to display these distinctions as they exhibit the highest power of all EEG frequency bands (Lozano-Soldevilla, 2018). The study used data from multiple online dataset repositories and direct solicitation from researchers. The datasets consisted of rest and task datasets. The task datasets employed a variety of cognitive domains (vigilance, executive attention, decision-making, working memory). For prediction, we used the Educated Temporal Prediction Algorithm, a novel, quick, accurate, and parameter-free phase detection algorithm, on each of these datasets to predict phase angles (Shirinpour et al., 2020). We then used a linear mixed effects model to identify the effect of rest and task on EEG phase prediction accuracy. Our results indicated that the eyes-closed resting state gives the highest accuracy (76.4%, 95% CI [75.0%, 77.9%]), followed by task states (74.7%, 95% CI [72.7%, 76.7%]) and then eyes-open resting state (72.81%, 95% CI [72.8%, 73.1%]). EEG signal power and signal-to-noise ratio (SNR) are significant covariates that also increase accuracy. As such, experiments involving real-time phase prediction may benefit from utilizing periods of high power and SNR in an eyes-closed resting condition.

In humans, steroids play a broad and vital role in regulation of gene expression, secondary sexual characteristics, maturation, reproduction, cardiovascular health, neurological functions, etc. Therefore, a complete profile of steroids in biological samples is essential to monitor human health. Steroid profiling is an effective tool to analyze different steroid related issues simultaneously in a single assay. Because of the blood stream's connection to saliva production, salivary steroid concentrations can be correlated to serum steroid concentration, making saliva a noteworthy alternative to evaluate systemic steroidogenesis. Clinically, saliva collection has the potential to provide a high-throughput, non-invasive, and inexpensive technique to evaluate steroid levels. However, global steroid metabolism in human saliva has not been thoroughly investigated. Therefore, the aim of the present study was to create individual steroid metabolome profiles of human saliva and use it to determine differences between males and normally-cycling females, between normally-cycling female's follicular and luteal phase, and between normally-cycling females and females on a form of birth-control.

Los informativos en el entorno digital contemporáneo cuentan con una serie de nuevas posibilidades para su conformación, para su difusión diversificada y oportuna, y para convocar e involucrar de modos diferentes y creativos a sus audiencias. Éstas, a su vez, cada vez más se involucran activamente con la información, no sólo en su recepción como ha sido siempre, sino en su producción y emisión también, interactuando de maneras imprevisibles con ella, ampliándola, reconstruyéndola, reinventándola y corrigiéndola, pero manteniéndola en circulación con diversos grados de modificación. Los autores reunidos en este libro contribuyen, desde sus posiciones e interacciones, con información para entender aspectos particulares de lo informativo.

The book "TransMath - Innovative Solutions from Mathematical Technology" has been conceived as a tool for the dissemination of scientific knowledge. This publication is addressed to those companies with innovation needs that could be met through mathematical technology. The book maps both existing and possible interactions and connections that enable technology transfer between Spanish mathematical research and industrial and business sectors. Businesses can determine the level of implementation and demand for such technology within their sector and understand the benefits and innovations achieved in other companies and industries with the application of mathematical techniques. The information is classified into eleven sectors of economic activity: Biomedicine & Health; Construction; Economics & Finance; Energy & Environment; Food; ICT; Logistics & Transport; Management & Tourism; Metal & Machinery; Public Administration; and Technical Services.

¿Qué es el vuelo de la vida? El vuelo de la vida es honrar la propia existencia, que en sí misma es completa, justa y dadivosa, consagrada al sentir sin miedo ni prisa. Sin embargo, nos embarcamos sin preparación alguna y sin manual de instrucciones, pero sí con identidad. En la aviación, la ruta a transitar, además de la altitud y la velocidad, está definida por el plan de vuelo. Debido a esto, tanto pilotos, tripulantes como pasajeros vivimos la emoción de surcar los cielos para llegar a la tierra en pleno uso del menos frecuente de los sentidos; el sentido común. El plan de desplazamiento para nosotros, viajeros de paso en este mundo, está determinado por la misión de vida; descubrirla es el viaje que todo ser humano debe emprender, de acuerdo con el itinerario establecido entre el primer aliento y el último suspiro, según las creencias de cada uno. Todos sin distingo de raza, religión o credo, en la cotidianidad hacemos escala en los distintos aeropuertos llamados emociones; miedo, angustia, rabia y tristeza y alegría. Aprendemos porque nos equivocamos, por ende con fe rectificamos el rumbo y la altitud. Finalmente, aterrizaremos en la pista del darnos cuenta de lo que debemos y nos corresponde realizar. El lugar donde la verdadera consciencia situacional despierta, conduciéndonos a la terminal del discernimiento con la brújula de la sabiduría entre la luz proporcionada por el espíritu y las sombras del ego, el amor y el perdón. ¿Cómo lo logramos?, las anécdotas y analogías aquí redactadas, podrían servir como punto de partida para motivarse y adentrarse en el mayor de los riesgos; saber y experimentar la gratitud de vivir en función de la voz melodiosa de nuestro ser interior... ¡BIENVENIDO AL VUELO DE LA VIDA!