Search

Nuclear Magnetic Resonance (NMR) has proved to be a uniquely powerful and versatile tool for analyzing and characterizing chemicals and materials of all kinds. This book focuses on the latest developments and applications for "solid-state" NMR, which has found new uses from archaeology to crystallography to biomaterials and pharmaceutical science research. The book will provide materials engineers, analytical chemists, and physicists, in and out of lab, a survey of the techniques and the essential tools of solid-state NMR, together with a practical guide on applications. In this concise introduction to the growing field of solid-state nuclear magnetic resonance spectroscopy the reader will find: Basic NMR concepts for solids, including guidance on the spin-1/2 nuclei concept Coverage of the quantum mechanics aspects of solid state NMR and an introduction to the concept of quadrupolar nuclei An understanding relaxation, exchange and quantitation in NMR An analysis and interpretation of NMR data, with examples from crystallography studies Appendices covering spin properties of spin-1/2 nuclides as well as NMR simulation procedures

The power of nuclear magnetic resonance, NMR, for characterizing molecules dissolved in solution is widely acknowledged and NMR forms an essential component of undergraduate chemistry degrees. However, the application of NMR to the solid state is much less well appreciated. This text sets out the fundamental principles of solid-state NMR, explaining how NMR in solids differs from that in solution, showing how the various interactions of NMR can be manipulated to yield high-resolution spectra and to give information on local structure and dynamics in solids. This book aims to take some of the mystique out of solid-state NMR by providing a comprehensible discussion of the methodology, including the basic concepts and a practical guide to implementation of the experiments. A basic knowledge of solution-state NMR is assumed and is only briefly covered. The text is intended for those in academia and industry expecting to use solid-state NMR in their research and looking for an accessible introduction to the field. It will also be valuable for non-experts interested in learning how NMR can be usefully applied to solid systems. Detailed mathematical treatments are delayed to a chapter at the mid-point of the text and can be skipped. Introductions to experiments and numerical simulations are provided to help link NMR results to experimental practice. The different aspects of solid-state NMR, from basic pulse-and-acquire experiments to sophisticated techniques for the measurement of anisotropy information are presented. Examples illustrate the wide variety of applications of the technique and its complementarity to other solid-state characterization techniques such as X-ray diffraction. Various aspects of NMR crystallography are covered as are topics of motion in solids.

New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future.* Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields

This first Australian edition of Teaching Primary English has been updated and adapted to reflect the Australian sociocultural and educational context. This text provides a comprehensive, evidence informed introduction to teaching and learning English in the primary school classroom. New content refers to the Australian English Curriculum and incorporates Aboriginal and Torres Strait Islander perspectives and literacy perspectives relevant to the Asia-Pacific region as well as the broader international context. This edition also includes a new section devoted to visual literacy, critical literacy and multimodality. Teaching advice and ideas are supported by practical examples linked to video clips filmed in real schools, reflective activities, observational tasks and online resources. Each section includes suggestions for great children’s literature and offers assessment advice and support for planning for diversity and special educational needs. Drawing on the very latest research and theory, supported by practical examples and guidance, this is an essential resource for pre-service teachers as they develop subject knowledge and the skills and confidence to deliver effective and engaging classroom practice.

Gloucestershire 2: The Vale and the Forest of Dean and its companion, Gloucestershire I: The Cotswolds, provide a lively and uniquely comprehensive guide to the architecture of Gloucestershire. Alan Brooks's extensively revised and expanded editions of David Verey's original volumes bring together the latest research on a county unusually rich in attractive and interesting buildings. The area covered lies on both sides of the River Severn, rising from flat alluvial lands to the lower slopes of the Cotswold Escarpment on the east and the rough wooded hills of the Forest of Dean on the Welsh border, with its distinctive industrial inheritance. Architecture is generally more varied and unpredictable than in the Cotswolds: stone, timber, brick and stucco all have local strongholds. The Vale is most famous for its two great churches, Gloucester Cathedral and Tewkesbury Abbey, both Norman buildings with brilliantly inventive late medieval modifications. The other major settlement is the spa town of Cheltenham, with its fine parades of Regency terraces. Country houses include Thornbury Castle, greatest of Early Tudor private houses, timber-framed manors such as Preston Court, and the extravagantly Neo-Gothic Toddington; churches range from the enigmatic Anglo-Saxon pair at Deerhurst to Randall Wells's Arts-and-Crafts experiment at Kempley. Amongst the memorable post-war landmarks are the suspension bridges and nuclear power stations on the banks of the Severn, and Aztec West, one of the best British business parks, on the northern fringes of Bristol. Visitors and residents alike will find their understanding and enjoyment of west Gloucestershire transformed by this book.

Drama and Digital Arts Cultures is a critical guide to the new forms of playful exploration, co-creativity, and improvised performance made possible by digital networked media. Drawing on examples from games, education, online media, technology-enabled performance and the creative industries, the book uses the elements of applied drama to frame our understanding of digital cultures. Exploring the connected real-world and virtual spaces where young people are making and sharing digital content, it draws attention to the fundamental applied drama conventions that infuse and activate this networked culture. Challenging descriptions of drama and digital technology as binary opposites, the book maps common principles and practice grounded in role, embodiment, performance, play, and identity that are being amplified and enhanced by the affordances of online media. Drama and Digital Arts Cultures draws together extensive original research including interviews with game designers, media producers, educators, artists and makers at the heart of these new digital cultures. Young people discuss their own creative practices and products, providing insight into a complex and evolving world being transformed by digital technologies. A practical guide to the field, it contains case studies and examples of the intersections of drama conventions and networked cultures drawn from the US, Canada, UK, Netherlands, Singapore and Australia. Written for scholars, educators, students and 'makers' everywhere, Drama and Digital Arts Cultures provides a clear understanding of how young people are blending creativity and learning with the powerful and empowering conventions of drama to create new forms of multimodal and transmedia storytelling.

One of the most interesting questions in architectural history is why modern architecture emerged from the war-ravaged regions of central Europe and not the United States, whose techniques of mass production and mechanical products so inspired the first generation of modern architects like Le Corbusier, Mies van der Rohe, and Walter Gropius. In From Autos to Architecture, sociologist David Gartman offers a critical social history that shows how Fordist mass production and industrial architecture in America influenced European designers to an extent previously not understood. Drawing on Marxist economics, the Frankfurt School, and French sociologist Pierre Bourdieu, From Autos to Architecture deftly illustrates the different class structures and struggles of America and Europe. Examining architecture in the context of social conflicts, From Autos to Architecture offers a critical alternative to standard architectural histories focused on aesthetics alone.

English is central to the primary-school curriculum and successfully mastering the basics has a significant influence on pupils’ ability to learn and achieve their future goals. Now fully updated, English 5–11 provides comprehensive, up-to-date and creative guidance on teaching English in the primary school. Each chapter provides the busy teacher with indispensable advice and guidance, as well as opportunities to reflect upon current practice in the classroom. Key areas covered include: ■ language and literacy development; ■ grammar, punctuation and spelling; ■ talk for learning; ■ systematic synthetic phonics; ■ fiction, poetry and non-fiction; ■ drama and creativity; ■ teaching in a multilingual classroom; ■ ICT ■ Planning and assessment. This third edition reflects changes in government policy and gives greater attention knowledge about language and is closely related to the changing curriculum for primary English. The highly experienced authors are former literacy advisors and have frontline teaching, school-management and teacher-training experience. This book will be an invaluable resource for all trainee and practising teachers interested in teaching English in an accessible, contemporary and dynamic way.