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In these divided and divisive times, what is the future course for our politics? In this ground-breaking book, Nick Timothy, one of Britain’s leading conservative thinkers and commentators, explores the powerful forces driving great changes in our economy, society and democracy. Drawing on his experience at the top of government, Timothy traces the crisis of Western democracy back to both the mistaken assumptions of philosophical liberalism and the rise of ideological ultra-liberalism on left, right and centre. Sparing no sacred cows, he proposes a new kind of conservatism that respects personal freedom but also demands solidarity. He argues that only by rediscovering a unifying sense of the common good and restoring a mutual web of responsibilities between all citizens and institutions can we reject the extremes of economic and cultural liberalism, overcome our divisions, and remake one nation. He goes on to outline an ambitious practical plan for change, covering issues ranging from immigration to the regulation of Big Tech. Nick Timothy’s original, forensic and thought-provoking analysis is a must-read for anybody tired by the old dogmas of the liberal left, right and centre. It is a major contribution to the debate on the future of conservatism as it grapples with geopolitical shifts, cultural change, and economic uncertainty.

Newly streamlined and focused on quick-access, easy-to-digest content, Mulholland and Greenfield’s Surgery: Scientific Principles & Practice, 7th Edition, remains an invaluable resource for today’s residents and practicing surgeons. This gold standard text balances scientific advances with clinical practice, reflecting rapid changes, new technologies, and innovative techniques in today’s surgical care. New lead editor Dr. Justin Dimick and a team of expert editors and contributing authors bring a fresh perspective and vision to this classic reference.

Comprehensive in coverage this textbook, written by academics from leading institutions, discusses current developments and debates in modern health economics from an international perspective. Economic models are presented in detail, complemented by real-life explanations and analysis, and discussions of the influence of such theories on policymaking. Offering sound pedagogy and economic rigor, Health Economics focuses on building intuition alongside appropriate mathematical formality, translating technical language into accessible economic narrative. Rather than shying away from intellectual building blocks, students are introduced to technical and theoretical foundations and encouraged to apply these to inform empirical studies and wider policymaking. Health Economics provides: - A broad scope, featuring comparative health policy and empirical examples from around the world to help students relate the principles of health economics to everyday life - Coverage of topical issues such as the obesity epidemic, economic epidemiology, socioeconomic health disparities, and behavioural economics - A rich learning resource, complete with hundreds of exercises to help solidify and extend understanding. This book is designed for advanced undergraduate courses in health economics and policy but may also interest postgraduate students in economics, medicine and health policy. Accompanying online resources for this title can be found at bloomsburyonlineresources.com/health-economics. These resources are designed to support teaching and learning when using this textbook and are available at no extra cost.

From the early 1960s until 1980 New York's Conservative and Republican Parties battled on the editorial page, at the ballot box, and in the courts over the ideology of the GOP. New York State and the Rise of Modern Conservatism recounts the story of how New York, reputedly the most liberal of all states, played a critical role in conservatism's political ascendancy and in the redrawing, according to ideology, of the country's party lines. Examining the colorful personalities central to the transformation, including Governor Nelson Rockefeller, William F. Buckley Jr., John Lindsay, Roy Cohn, Jackie Robinson, Clare Booth Luce, G. Gordon Liddy, and William Casey, author Timothy J. Sullivan recounts the details of the party's battle, a battle that ultimately forced the state's liberal Republicans to choose between their party and their ideology, resulting in a reliably conservative national GOP prepared to nominate Ronald Reagan.

A chemocentric view of the molecular structures of antibiotics, their origins, actions, and major categories of resistance Antibiotics: Challenges, Mechanisms, Opportunities focuses on antibiotics as small organic molecules, from both natural and synthetic sources. Understanding the chemical scaffold and functional group structures of the major classes of clinically useful antibiotics is critical to understanding how antibiotics interact selectively with bacterial targets. This textbook details how classes of antibiotics interact with five known robust bacterial targets: cell wall assembly and maintenance, membrane integrity, protein synthesis, DNA and RNA information transfer, and the folate pathway to deoxythymidylate. It also addresses the universe of bacterial resistance, from the concept of the resistome to the three major mechanisms of resistance: antibiotic destruction, antibiotic active efflux, and alteration of antibiotic targets. Antibiotics also covers the biosynthetic machinery for the major classes of natural product antibiotics. Authors Christopher Walsh and Timothy Wencewicz provide compelling answers to these questions: What are antibiotics? Where do antibiotics come from? How do antibiotics work? Why do antibiotics stop working? How should our limited inventory of effective antibiotics be addressed? Antibiotics is a textbook for graduate courses in chemical biology, pharmacology, medicinal chemistry, and microbiology and biochemistry courses. It is also a valuable reference for microbiologists, biological and natural product chemists, pharmacologists, and research and development scientists.

The second edition of Corporate Real Estate Asset Management is fully up to date with the latest thought and practice on successful and efficient use of corporate office space. Written from an occupier’s perspective, the book presents a ten-point CREAM model that offers advice on issues such as sustainability, workplace productivity, real estate performance measurement, change management and customer focus. In addition, new case studies provide real-life examples of how corporations in the UK, USA, Hong Kong and Abu Dhabi actively manage their corporate real estate. The book is aimed at advanced undergraduate and graduate students on corporate real estate, facilities management and real estate courses and international MBA programmes.

Regardless of how the presidency of Donald J. Trump ultimately concludes, a significant part of its legacy will relate to the First Amendment. The president has publicly attacked the institutional press and individual reporters, calling them the "enemy of the people." He has proposed that flag burners be jailed and de-naturalized, blocked critics from his Twitter page, communicated hateful and derogatory ideas, and defended the speech of white nationalists. More than any other modern president, Trump has openly challenged fundamental First Amendment norms and principles relating to free speech and free press. These challenges have come at a time when the institutional press faces economic and other pressures that negatively affect their functions and legitimacy, political and other forms of polarization are on the rise, and protesters face diminished space and opportunities for exercising free speech rights. The First Amendment in the Trump Era catalogs and analyzes the various First Amendment conflicts that have occurred during the Trump presidency. It places these conflicts in historical context-as part of our current digitized and polarized era but also as part of a broader narrative concerning attacks on free speech and press. We must understand what is familiar in terms of the First Amendment concerns of the present era, but also what is distinctive about these concerns. The Trump Era has once again reminded us of the need for a free and independent press, the need to protect robust and sometimes caustic criticism of public officials, and the importance of protest and dissent to effective self-government.

A clear-eyed assessment of where we go from here—detailing how to combat misinformation and isolation—from the foremost expert on American political violence “A soulful and significant contribution to defeating the authoritarian threat in America.” — Congressman Jamie Raskin, author of Unthinkable: Trauma, Truth, and the Trials of American Democracy “Tim’s insights can help us reclaim a government that works for all Americans and restore faith in our democratic institutions.” — Barbara McQuade, author of Attack from Within: How Disinformation is Sabotaging America As the lead investigator into both the 2017 racist riot in Charlottesville and the January 6 insurrection, Tim Heaphy has a unique perspective on the cynicism and anger that also fueled Trump’s return to the Presidency. All 3 events, both the violent protests and the peaceful and lawful decisions made at the ballot box in November of 2024, reflect an increasing lack of trust in institutions among a growing number of Americans. In his page-turning book, Heaphy shares what he saw and came to understand about what those events say about the state of American democracy. He examines how and why they took place with the hope that understanding the contexts of these events will be a crucial and helpful step toward avoiding similar episodes of political violence in the years ahead. Readers will travel alongside Heaphy as he organized his team and structured the massive investigations they were about to undertake, as he interacts with politicians and members of law enforcement, interviews planners, perpetrators, and bystanders, gathers and sorts evidence, and compels and records testimony in order to create a record for today as well as future generations.