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This book contributes to better understand how lifestyle modulations can effectively halt the emergence and progression of human diseases. The book will allow the reader to gain a better understanding of the mechanisms by which the environment interferes with the bio-molecular regulatory processes underlying the emergence and progression of complex diseases, such as cancer. Focusing on key and early cellular bio-molecular events giving rise to the emergence of degenerative chronic disease, it builds on previous experience on the development of multi-cellular organisms, to propose a mathematical and computer based framework that allows the reader to analyze the complex interplay between bio-molecular processes and the (micro)-environment from an integrative, mechanistic, quantitative and dynamical perspective. Taking the wealth of empirical evidence that exists it will show how to build and analyze models of core regulatory networks involved in the emergence and progression of chronic degenerative diseases, using a bottom-up approach.

Reúne 26 trabajos que se enmarcan dentro de algunas de las más fructíferas líneas de trabajo de la lingüística actual: sociolingüística, dialectología, lexicografía, revisión crítica de córpora y usos discursivos.--Publisher's description.

The purpose of this Brief is to provide a global view of the concept of biopreservation and its potential and existing applications in the different food sectors. Biopreservation, an approach already experimented with by our ancestors, has been used empirically for centuries and now the rationale behind it is becoming increasingly popular, applied singly or in combination with novel and classical food processing technologies. The growing world population, together with the globalization of the food market and consumer demand for foods that are ready to eat, lightly preserved, fresh-tasting, and rich in flavor, nutrients, and bioactive compounds, is forcing the food industry to develop less aggressive food preservation methods.

Recent advances in molecular and cellular biology have markedly changed our understanding of the heart, and this is having tremendous ramifications for the clinician. This unique reference offers a comprehensive and critical evaluation of this contribution in the field of cardiovascular molecular medicine providing the reader with a sense of new directions in which molecular medicine might be applied. It begins with a detailed primer that makes readily accessible recent molecular, genetic and cellular techniques. Rounding out the coverage of this exciting field are critical and comprenhesive discussions on the use of molecular, genetic and cellular techniques used to identify the etiology and pathophysiology of specific cardiac diseases.* Discusses diagnostic and therapeutic options available not only in the adult and aging individuals but also in infants/children* Numerous illustrations and flow-charts* Explans cutting-edge molecular techniques, including analysis of mitochondria, their role in cardiac dysfunction and updated analysis of Cardioprotection and Metabolic Syndrome* Presentation of recent translational studies for the treatment of cardiovascular diseases is included (e.g., gene therapy, pharmacological treatments and stem cell transplantation)

To get to know in greater detail the history of Opus Dei and its founder: to get to know the central characters, what its documents say, its influence on the Catholic Church and contemporary society. Since 2007, this has benn the task of the journal "Studia et Documenta". The journal gathers together studies, annotated unpublished documents, news of academic interest, reviews and synopses, and a comprehensive bibliographic bulletin. Each volume contains in the region of 500 pages. The articles are prepared by specialists and are subjected to the peer review system.

Beginning from the premise that being non-racist – and other ‘neutral’ positions – are inadequate in the face of a racist society and institutions, this book provides language educators with practical tools to implement antiracist pedagogy in their classrooms. It offers readers a solid theoretical grounding for its practical suggestions, drawing on work in critical race theory, critical sociolinguistics and language ideology to support its argument for antiracist pedagogy as a necessary form of direct action. The author contends that antiracist pedagogy is a crucial part of the project of decolonizing universities, which goes beyond tokenistic diversity initiatives and combats racism in institutions that have historically helped to perpetuate it. The author’s pedagogical suggestions are accompanied by online resources which will help the reader to adapt and develop the material in the book for their own classrooms.

Advances in the study of dynamical systems have revolutionized the way that classical mechanics is taught and understood. Classical Dynamics, first published in 1998, is a comprehensive textbook that provides a complete description of this fundamental branch of physics. The authors cover all the material that one would expect to find in a standard graduate course: Lagrangian and Hamiltonian dynamics, canonical transformations, the Hamilton-Jacobi equation, perturbation methods, and rigid bodies. They also deal with more advanced topics such as the relativistic Kepler problem, Liouville and Darboux theorems, and inverse and chaotic scattering. A key feature of the book is the early introduction of geometric (differential manifold) ideas, as well as detailed treatment of topics in nonlinear dynamics (such as the KAM theorem) and continuum dynamics (including solitons). The book contains many worked examples and over 200 homework exercises. It will be an ideal textbook for graduate students of physics, applied mathematics, theoretical chemistry, and engineering, as well as a useful reference for researchers in these fields. A solutions manual is available exclusively for instructors.

Our future scientists and professionals must be conversant in computational techniques. In order to facilitate integration of computer methods into existing physics courses, this textbook offers a large number of worked examples and problems with fully guided solutions in Python as well as other languages (Mathematica, Java, C, Fortran, and Maple). It’s also intended as a self-study guide for learning how to use computer methods in physics. The authors include an introductory chapter on numerical tools and indication of computational and physics difficulty level for each problem. Readers also benefit from the following features: • Detailed explanations and solutions in various coding languages. • Problems are ranked based on computational and physics difficulty. • Basics of numerical methods covered in an introductory chapter. • Programming guidance via flowcharts and pseudocode. Rubin Landau is a Distinguished Professor Emeritus in the Department of Physics at Oregon State University in Corvallis and a Fellow of the American Physical Society (Division of Computational Physics). Manuel Jose Paez-Mejia is a Professor of Physics at Universidad de Antioquia in Medellín, Colombia.