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This comprehensive textbook presents a systematic account of the effects, both good and bad, of the immune system. Special emphasis is placed on what the immune system actually does in causing and preventing disease. The fifth edition is divided into three parts discussing the fundamentals of immune mechanisms, the seven immunologic effector mechanisms contrasted and compared, and how the immune mechanisms act in disease and cancer. A new chapter on HIV infection and AIDS has been included.

Despite its idyllic setting, the coast of the Pacific Northwest has another, darker name by which it is known: the "Graveyard of the Pacific." Two thousand ships and countless lives have been lost to the waters of the Pacific Ocean, and the Columbia River has claimed many more. The spirits of early settlers, Native Americans and drowned mariners are said to linger near the shores. From ghostly treasure hunters eternally searching for buried gold to a graveyard filled with souls that met violent ends, legends abound. Join author Ira Wesley Kitmacher as he uncovers mysterious tales and takes readers on a road trip through this most haunted place in America.

Fluorine continues to intrigue chemists who overcome the challenge of handling this remarkable halogen and work to develop varied methods for synthesising fluorine compounds. The unique properties of these materials, ranging from inert perfluorocarbons and fluoropolymers to a multitude of other fascinating fluorinated compounds, firmly established their place amidst the technological achievements of the 20th Century. Fluorine substitution in biologically active compounds has become particularly significant in recent years. This book presents new and significant research in this field.

As progressively more farmers in developing countries begin using biotech crops, careful evaluation of such crops' benefits becomes ever more important.This food policy review examines the applied economics literature regarding the impact of biotech crops on non-industrialized agriculture, and investigates the research methods used in assessing how these crops affect farmers, consumers, the agricultural sector as a whole, and international trade. This analysis offers a tool for researchers who seek to produce objective, relevant analysis of emerging crop biotechnologies that can in turn be used by national policymakers in developing countries.

Forensic mental health assessment (FMHA) has grown into a specialization informed by research and professional guidelines. This series presents up-to-date information on the most important and frequently conducted forms of FMHA. The 19 topical volumes address best approaches to practice for particular types of evaluation in the criminal, civil and juvenile/family areas. Each volume contains a thorough discussion of the relevant legal and psychological concepts, followed by a step-by-step description of the assessment process from preparing for the evaluation to writing the report and testifying in court. Volumes include the following helpful features: - Boxes that zero in on important information for use in evaluations - Tips for best practice and cautions against common pitfalls - Highlighting of relevant case law and statutes - Separate list of assessment tools for easy reference - Helpful glossary of key terms for the particular topic In making recommendations for best practice, authos consider empirical support, legal relevance, and consistency with ethical and professional standards. These volumes offer invaluable guidance for anyone involved in conducting or using forensic evaluations.

This issue of Dental Clinics of North America points the dental profession in the direction of greater coordination with the health care system for chronic diseases like hypertension, diabetes mellitus, osteoporosis, obesity, and by promoting smoking cessation and a healthy lifestyle.

Religious conversion - a shift in membership from one community of faith to another - can take diverse forms in radically different circumstances. As the essays in this volume demonstrate, conversion can be protracted or sudden, voluntary or coerced, small-scale or large. It may be the result of active missionary efforts, instrumental decisions, or intellectual or spiritual attraction to a different doctrine and practices. In order to investigate these multiple meanings, and how they may differ across time and space, this collection ranges far and wide across medieval and early modern Europe and beyond. From early Christian pilgrims to fifteenth-century Ethiopia; from the Islamisation of the eastern Mediterranean to Reformation Germany, the volume highlights salient features and key concepts that define religious conversion, particular the Jewish, Muslim and Christian experiences. By probing similarities and variations, continuities and fissures, the volume also extends the range of conversion to focus on matters less commonly examined, such as competition for the meaning of sacred space, changes to bodies, patterns of gender, and the ways conversion has been understood and narrated by actors and observers. In so doing, it promotes a layered approach that deepens inquiry by identifying and suggesting constellations of elements that both compose particular instances of conversion and help make systematic comparisons possible by indicating how to ask comparable questions of often vastly different situations.