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Molecular and Cellular Therapeutics aims to bring together key developments in the areas of molecular diagnostics, therapeutics and drug discovery. The book covers topics including diagnostics, therapeutics, model systems, clinical trials and drug discovery. The developing approaches to molecular and cellular therapies, diagnostics and drug discovery are presented in the context of the pathologies they are devised to treat.

The World Today Series: USA and The World describes not only what happened, but puts events in the context of the past and criticizes policy actions as appropriate. The result goes deeper than most of what appears in current publications. Updated annually and part of the renowned “World Today Series,” USA and the World presents an unusually penetrating look into America and its relationship to the rest of the world. The combination of factual accuracy and up-to-date detail along with its informed projections make this an outstanding resource for researchers, practitioners in international development, media professionals, government officials, potential investors and students. Now in its 19th edition, the content is thorough yet perfect for a one-semester introductory course or general library reference.

This bold new theoretical study explores dissident subjectivity, that is, the struggle for unique authorial identity in American literary discourse that has existed, according to David Jarraway, since the Romantics. From Emerson’s “Experience” remarking upon the “focal distance within the actual horizon of human life” to Toni Morrison’s Nobel Prize address sanctifying the artist’s “sophisticated privileged space,” American literature has continuously recognized a necessary “distance”—the gap between culturally accepted ideas of selfhood and the intractable reality of the self’s never-completed construction in time. Jarraway’s fascinating examination of modernist poets shows that engaging with this artistic space, or “going the distance,” empowers writers and their readers to create and perceive identities that resist the frozen certainties of conventional gender, sexual, and social roles. Employing this theory with grace and precision, Jarraway ranges through the dissident process in Gertrude Stein, the cultural criticism of William Carlos Williams, the deferred racialism of Langston Hughes, the queer perversities of Frank O’Hara, and the spectral lesbian poetics of Elizabeth Bishop. Bolstered further by insights from the pragmatism of William James through the cultural critique of Theodor Adorno to the queer theory of Judith Butler, the author challenges his audience with politically engaged insistence on the life-affirming potentialities of human subjectivity in literature. His passionate conclusion demonstrates the liberating fluidity of self made possible by feminist chartings of modern identity’s depths. Lucidly composed, theoretically sophisticated and up-to-the-minute, Going the Distance painstakingly recovers the dissident American subjective in modernist literary discourse within its fullest cultural context. Jarraway’s readings are a major contribution to poetry scholarship and to cultural studies that will provoke further investigations into the history of subjectivity in American literature as a whole.

An entirely new interpretation of modern American portraiture based on the history of sexual difference. Hide/Seek: Difference and Desire in American Portraiture, companion volume to an exhibition of the same name at the National Portrait Gallery, Smithsonian Institution, traces the defining presence of same-sex desire in American portraiture through a seductive selection of more than 140 full-color illustrations, drawings, and portraits from leading American artists. Arcing from the turn of the twentieth century, through the emergence of the modern gay liberation movement in 1969, the tragedies of the AIDS epidemic, and to the present, Hide/Seek openly considers what has long been suppressed or tacitly ignored, even by the most progressive sectors of our society: the influence of gay and lesbian artists in creating American modernism. Hide/Seek shows how questions of gender and sexual identity dramatically shaped the artistic practices of influential American artists such as Thomas Eakins, Romaine Brooks, Marsden Hartley, Georgia O'Keeffe, Charles Demuth, Jasper Johns, Robert Rauschenberg, Andrew Wyeth, Andy Warhol, Robert Mapplethorpe, and many more—in addition to artists of more recent works such as Felix Gonzalez-Torres, Glenn Ligon, Catherine Opie, and Cass Bird. The authors argue that despite the late-nineteenth-century definition and legal codification of the “homosexual,” in reality, questions of sexuality always remained fluid and continually redefined by artists concerned with the act of portrayal. In particular, gay and lesbian artists—of but not fully in the society they portrayed—occupied a position of influential marginality, from which vantage point they crafted innovative and revolutionary ways of painting portraits. Their resistance to society's attempt to proscribe them forced them to develop new visual vocabularies by which to code, disguise, and thereby express their subjects' identities—and also their own. Bringing together for the first time new scholarship in the history of American sexuality and new research in American portraiture, Hide/Seek charts the heretofore hidden impact of gay and lesbian artists on American art and portraiture and creates the basis for the necessary reassessment of the careers of major American artists—both gay and straight—as well as of portraiture itself.

An examination of the continuities and differences between American Impressionism and Realism. Copyright © Libri GmbH. All rights reserved.

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The Neurology of Eye Movements provides clinicians with a synthesis of current scientific information that can be applied to the diagnosis and treatment of disorders of ocular motility. Basic scientists will also benefit from descriptions of how data from anatomical, electrophysiological, pharmacological, and imaging studies can be directly applied to the study of disease. By critically reviewing such basic studies, the authors build a conceptual framework that can be applied to the interpretation of abnormal ocular motor behavior at the bedside. These syntheses are summarized in displays, new figures, schematics and tables. Early chapters discuss the visual need and neural basis for each functional class of eye movements. Two large chapters deal with the evaluation of double vision and systematically evaluate how many disorders of the central nervous system affect eye movements. This edition has been extensively rewritten, and contains many new figures and an up-to-date section on the treatment of abnormal eye movements such as nystagmus. A major innovation has been the development of an option to read the book from a compact disc, make use of hypertext links (which bridge basic science to clinical issues), and view the major disorders of eye movements in over 60 video clips. This volume will provide pertinent, up-to-date information to neurologists, neuroscientists, ophthalmologists, visual scientists, otalaryngologists, optometrists, biomedical engineers, and psychologists.

"Designed for graduate level courses in adult psychopathology, the Second Edition of this book incorporates the newly released (2013) DSM-5 . Unique in its approach, this text presents a historical context in which current diagnoses are made. Presenting an overview of the issues and methodologies of conducting assessments, each of the major psychological disorders is discussed in a standard format in the chapter dealing with that disorder. The text includes new chapters on nonalcohol substance abuse and contextual factors affecting diagnoses. Each chapter covers: description from DSM, using case examples; epidemiology; basic research, including neurobiology and neuroscience of the disorder; prevalence and consequences of the disorder; behavioral, social, cognitive, and emotional aspects of the disorder; and treatment of the disorder, using clinical examples showing how psychopathology and assessment influence treatment"--