Search

QSAR methods and stereoselectivity in action; QSAR, a European viewpoint; Consequences of the Hansch Paradigm, part 2; Comparative structure-activity relationships; Some problems of the interpretation of receptorologic data in QSAR work; Quantitative and explicit structure-time-activity relations; QSAR analysis of chiral compounds including racemates; Surface area and hydrophobicity of small molecules; Increasing the accuracy of computer calculated log P (Oct/Water) values; Titrations in water-saturated octanol, a guide to partition coefficients of ion pairs and receptor-site interactions; Quantitative structure affinity relationships in a series of alpha-2 adrenergic amines using the molecular lipophilicity potential; Lipophilicity and conformational behavior of substituted Xanthines; Determination of the partition coefficients of adamantyl derivatives by reversed phase TLC and HPLC; Comparison between measured and calculated partition coefficients of beta-receptor antagonists; Benzenesulfonamide inhibitors of carbonic anhydrase, study of their hydrophobicity by RPLC; Partition coefficients of diazines; Lipophilicity of a series of cytostatic aziridinyl quinones; QSAR parameters a la carte from computer chemistry; CISOC-SARSS, a versatile structure-activity relationship study system; DESBASE, a multiparameter substituent database; An index of flexibility from molecular shape descriptors; A new type of information index and its use; QSAR and multivariate data analysis of the interaction of amphiphilic drugs with phospholipids; Multivariate data analyses of QSAR parameters; Principal properties of aromatic substituents; Multivariate parametrization of coded and non-coded amino acids by thin layer chromatography; Response surfaces for modelling biological activities by principal properties of substituents, The Carso Procedure; Analogy in computer-assisted design; Automatic knowledge base building for the organic synthesis design program (SECS); Molecular shape analysis of structure-activity tables; Recent advances in comparative molecular field analysis (CoMFA); Molecular similarity, a basis for designing drug screening programs; Implementing drug screening programs using molecular similarity methods; Strategies in drug design based on 3D structures of ligands; Logic-based methods for drug design; The use of 3D modelling databases for identifying structure-activity relationships; QSAR oriented computer representation of chemical compounds used in CISOC-SARSS; Discovering activity determinants, graphics and a related probability; DARC/PELCO success in anticholinergic research; Antineoplastic activity prediction by means of a statistical-heuristic technique; QSAR analysis of acetylcholinesterase inhibitors by use of structure similarity methods; Structural databases and computer modeling in pharmaceutical research; Computer aided peptide and protein engineering; Molecular modeling of beta-cyclodextrin drug inclusion complexes based on NMR interaction measurements; Molecular modelling of the interaction of dihydropyridine drugs with their receptors; Computer aided molecular modelling applied by the dopaminergic system; Conformational analysis of antifolates, molecular structure and enzyme binding of the 4'-COOH trimethoprim derivative; Molecular modelling of inhibitors and herbicides for photosynthetic systems; Common conformational and electronic features for nondihydropyridines calcium antagonists; Molecular electrostatic potentials, a critical assessment in QSAR and a tryptamine binding model; Beta-adrenoceptor modeling based on MEP studies; Electrostatic potential maps of enzyme inhibitors; Binding of agonists and antagonists to beta-adrenergic receptor; Why are benzocycloheptenylamines inactive as dopamine D2-receptor agonists; Mechanism based analysis of enzyme inhibitors of amide bond hydrolysis; Cholecystokinin inhibitors, a combined QSAR and molecular graphic analysis; Cyclosporine, intrinsic binding energies to interpre structure-activity relationships; Quantification of peptide bioactivities, peptide antibiotics; Peptide QSARs, PLS modelling and design in principal properties; Sweet taste receptor recognition of the conformationally flexible aldoxime molecule; Conformational study of erythromycin analogues; Conformational analysis of fenpropimorph; 3D-QSAR, towards a quantitative three dimensional description of muscarinic agonists; QSAR study in xenobiotics distribution-estimation of target organ; The structure selectivity problem in drug design with respect to antifolates; Comparative QSAR analysis in dihydropteroate synthase inhibition by sulphones, design and synthesis of some new derivatives with improved potency; Structure-activity studies of chemical carcinogens in non-congeneric sets of compounds; QSAR study of analgesic and anti-inflammatory potencies of commercially available non-steroidal anti-inflammatory drugs (NSAIDs); Use of QSAR in design of anti-inflammatory arylalkanoic acids; A QSAR study of a series of beta-carbolines; Theoretical study of the tautomerism of adenosine and formycin, functional implications; QSAR on substituted salicylamides; Structure-activity relationships of H2-receptor histamine antagonists based on quantum chemical methods; Design, synthesis, and SAR of analgesics; A Free-Wilson analysis of the calcium channel blocking activity of some dihydropyridines; On the use of 1H-NMR and 13C-NMR chemical shifts in a QSAR of benzotriazole derivatives; Statistical analysis of electronic absorption spectra of N-methylpyrazoles; The application of Free-Wilson models in spectroscopy of pyrazoles, delta-H4 1H-NMR; QSAR in olfaction, ambergris type odorants; Correlation of hydrophobicity and molecular connectivities with toxicities of chlorobenzenes to different species; Modeling environmental distribution of organic pollutants; QSARs and pesticides design; A QSAR study of Overton's tadpole data.

Mills & Boon Intrigue — Seek thrills. Solve crimes. Justice served. Set Up in the City - B.J. Daniels Deputy Willie Colt feels at home in the wide-open spaces of Montana. Attorney Eleanor Shaffer has a corner office with a spectacular view of Seattle. He was brutally attacked while trying to extradite her client. And though Willie and Elleanor have every reason to distrust each other, they’ll have to work together if they’re going to mete out justice. Move over big city tactics — and meet good old cowboy grit. Rescued by the Rancher - Barb Han When rancher Callum Hayes learns that Payton Reinert has returned to Cider Creek, Texas, to hide out from a killer, he opens his family home to her and her rescue dog. Though reluctant to offer his heart — broken by betrayal — he can’t ignore his electrifying attraction to the vulnerable beauty and his desire to protect her. Even if stopping the monstrous killer means risking his life… Shot in the Dark - Nicole Helm Henry Thompson is a former marine — not a babysitter. But when Jessie Peterson begs for his help locating her rebellious preteen, his military-rescue instincts kick into overdrive. The desperate single mum has stumbled onto family treasure, buried secrets, deadly doppelgängers…and imminent danger. With gunfire dogging their every move, Henry will do anything to keep them safe. But will he lose his guarded heart in the bargain? Catching the Carling Lake Killer - K.D. Richards Journalist Simone Jarrett and Carling Lake Sheriff Lance Webb have kept their casual affair clandestine to avoid gossip. But as his feelings for Simone deepen, Lance is troubled by the knowledge that she’s hiding something. Then, after twenty years, the Card Killer strikes again. And Simone’s secret puts her in the killer’s sights. Now the two must team up to find the murderer…and save Simone’s life. Texas Bodyguard: Brax - Janie Crouch A skilled security expert and bodyguard, Brax Patterson is ready for anything…except unexpected custody of his reckless half brother’s baby boy. Someone will kill to take young Walker — and silence his resourceful new nanny, Tessa Mahoney. With her help, Brax is breaking all the rules to keep them safe. But will his and Tessa’s shattering secrets prove too lethal to survive? Resolute Aim - Leslie Marshman Traumatised after killing in self-defence, Bree Delgado left San Antonio PD to join a rural sheriff’s office. Her distractingly gorgeous new partner, Noah Reed, assures her that small towns have serious crime, too — and Bree has a dangerous vulnerability. She may have to trust Noah with the truth, but that doesn’t mean she has to give in to the attraction simmering between them…