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Leela and Liam want to visit their favorite spots at the Metropolitan Museum of Art on their class trip, but when their teacher and tour guide have different plans, they realize new discoveries can be just as sweet as old traditions. Aligned to Common Core Standards and correlated to state standards. Calico Kid is an imprint of Magic Wagon, a division of ABDO.

When faced with the possible closing of her favorite beach, Sylvie first attempts a one-person coastal cleanup march on city hall, but thanks to the town clown, she realizes it will take more than one person to save the beach. Aligned to Common Core standards and correlated to state standards. Calico is an imprint of Magic Wagon, a division of ABDO.

Sylvie wants to win her school's talent show so she can be featured in the local newspaper to garner buzz for her coat drive, but she struggles to figure out her talent. Aligned to Common Core standards and correlated to state standards.

Sylvie's excitement for the upcoming Earth Day Extravaganza fizzles when her cousin, the non-recycler, visits, and she worries about not only saving the entire world, but the extravaganza itself. Aligned to Common Core standards and correlated to state standards. Calico is an imprint of Magic Wagon, a division of ABDO.

"Sylvie wants to win her school's talent show so she can be featured in the local newspaper to garner buzz for her coat drive, but she struggles to figure out her talent."--Back cover

Sylvie can't wait to raise money for the animal shelter for her Make a Difference Day project, but with her frenemy, Camilla, and Sylvie's foster puppy creating obstacles along the way, she discovers there is more than one way to make a difference. Aligned to Common Core standards and correlated to state standards.

Mycoplasma bovis associated diseases are newly emerging causing significant economic losses in the cattle industry. Therefore, it is necessary to understand the pathogenesis of M. bovis to develop new preventive methods to this group of diseases. The major research focus reported herein was to better understand the interactive impairment of the cattle's immune system by stress and M. bovis and subsequent increase in Mycoplasma bovis associated diseases. The first specific objective was to develop a stress model to study impairment of the bovine immune system as reflected by M. bovis shedding in colonized calves. Two experimental trials to mimic the effect of stress through synthetic glucocorticoid administration (dexamethasone) on M. bovis shedding were conducted. Results of both trials showed that the onset, the duration, and the likelihood of calves shedding M. bovis, were significantly greater in dexamethasone treated calves compared to controls. Through the second and third objectives, we evaluated neutrophil functions as affected by dexamethasone and four opsonized M. bovis strains or dexamethasone and four unopsonized M. bovis strains respectively. Dexamethasone consistently decreased all neutrophil functions tested with opsonized or unopsonized M. bovis . There were strain and strain by treatment interaction effects on some neutrophil functions. This interaction had an additive effect on neutrophil killing. The interaction of M. bovis and dexamethasone on bovine neutrophil killing might explain in part the association of stressful events with subsequent outbreaks of Mycoplasma bovis associated diseases. The stress model may aid in further study of the interaction between M. bovis and stress for evaluating new control measures for M. bovis infection in cattle.