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A pragmatic guide for developing your own games with Python About This Book Strengthen your fundamentals of game programming with Python language Seven hands-on games to create 2D and 3D games rapidly from scratch Illustrative guide to explore the different GUI libraries for building your games Who This Book Is For If you have ever wanted to create casual games in Python and you would like to explore various GUI technologies that this language offers, this is the book for you. This title is intended for beginners to Python with little or no knowledge of game development, and it covers step by step how to build seven different games, from the well-known Space Invaders to a classical 3D platformer. What You Will Learn Take advantage of Python's clean syntax to build games quickly Discover distinct frameworks for developing graphical applications Implement non-player characters (NPCs) with autonomous and seemingly intelligent behaviors Design and code some popular games like Pong and tower defense Compose maps and levels for your sprite-based games in an easy manner Modularize and apply object-oriented principles during the design of your games Exploit libraries like Chimpunk2D, cocos2d, and Tkinter Create natural user interfaces (NUIs), using a camera and computer vision algorithms to interpret the player's real-world actions In Detail With a growing interest in learning to program, game development is an appealing topic for getting started with coding. From geometry to basic Artificial Intelligence algorithms, there are plenty of concepts that can be applied in almost every game. Python is a widely used general-purpose, high-level programming language. It provides constructs intended to enable clear programs on both a small and large scale. It is the third most popular language whose grammatical syntax is not predominantly based on C. Python is also very easy to code and is also highly flexible, which is exactly what is required for game development. The user-friendliness of this language allows beginners to code games without too much effort or training. Python also works with very little code and in most cases uses the “use cases” approach, reserving lengthy explicit coding for outliers and exceptions, making game development an achievable feat. Python Game Programming by Example enables readers to develop cool and popular games in Python without having in-depth programming knowledge of Python. The book includes seven hands-on projects developed with several well-known Python packages, as well as a comprehensive explanation about the theory and design of each game. It will teach readers about the techniques of game design and coding of some popular games like Pong and tower defense. Thereafter, it will allow readers to add levels of complexities to make the games more fun and realistic using 3D. At the end of the book, you will have added several GUI libraries like Chimpunk2D, cocos2d, and Tkinter in your tool belt, as well as a handful of recipes and algorithms for developing games with Python. Style and approach This book is an example-based guide that will teach you to build games using Python. This book follows a step-by-step approach as it is aimed at beginners who would like to get started with basic game development. By the end of this book you will be competent game developers with good knowledge of programming in Python.

Coenzyme Q10 (CoQ) deficiencies are clinically and genetically heterogeneous diseases that can occur due to defects of ubiquinone biosynthesis (primary deficiencies) or other causes (secondary deficiencies). Radical oxygen species (ROS) production and oxidative stress is a common consequence of dysfunctional mitochondria and CoQ deficiency. Mitochondrial damage induced by ROS can trigger mitochondrial permeability transition (MPT) by opening of non-specific high conductance permeability transition pores in the mitochondrial inner membrane. This, in turn, leads to a simultaneous collapse of mitochondrial membrane potential and the activation of selective elimination of depolarized and dysfunctional mitochondria by mitophagy. In this respect, mitophagy could be considered as a protective mechanism for elimination of potential harmful mitochondria. Mitophagy must be accompanied by mitochondrial biogenesis activation to compensate the mitochondrial loss. However, massive and persistent mitophagy may impair cell bioenergetics, autophagy flux, and mitochondrial biogenesis, and eventually may cause cell death.

The new winner of the Paz Prize for Poetry, granted by the National Poetry Series, is the author’s impressionistic homage to his hometown of Colima, Mexico. “In this remarkable bilingual debut . . . Pérez-Cortés cracks open the name of his hometown, Colima, to generate a vast mythology . . . The side-by-side presentation of the original Spanish and its English translation adds another layer to this engrossing volume.” —Booklist A Poets & Writers Page One Selection Ima and Coli Are the Tree That Was Never a Seed is Alejandro Pérez-Cortés’s personal genesis of Colima, Mexico, published here in both English and Spanish. The tree is an element/character in the book that appears and disappears throughout. Some poems are set in an ancient pre-Hispanic Colima; others reflect the reality of a modern-day Colima, sadly stigmatized and eroded by violence perpetrated by the narcos. In his introduction, preeminent Cuban poet José Kozer praises Pérez-Cortés: “Ima and Coli Are the Tree That Was Never a Seed comprises a voice that I consider poetic and that should be cared for and listened to with true interest. A voice that encompasses all, one that seeks to integrate, remake, and modify normative language when necessary, and to distort language that allows a better perception of the present and of everything that is historically behind a contemporary poet.” The Paz Prize for Poetry is presented by the National Poetry Series and Miami Book Fair at Miami Dade College and is awarded biennially. Named in the spirit of the late Nobel Prize–winning poet Octavio Paz, it honors a previously unpublished book of poetry written originally in Spanish by an American resident.

This dissertation traces how undocumented, non-Jewish Latin American labor migrants and their children in Israel are transformed into a group which is conscious that their ethnic distinction is related to their discourse, a process which simultaneously transforms their discourse. In the last two decades, non-Jewish labor migration from many parts of the world has completely changed Israel's labor market and socio-space. In considering the Latinos discursive transformation, the dissertation follows several twentieth-century theoretical trajectories which have studied how the emergence of a sociologically-distinct group is accompanied by, and indeed crystallizes in, the equally emergent process of constituting registers and genres. Following a linguistic anthropological concern with textuality, it takes an explicitly Bakhtinian look at questions of Latinos' discursive shifts in multilingual domestic settings (e.g., codeswitching and borrowing), of their relation to the public circulation of gossip, and of their relation to a larger, news-mediated Israeli public. Each of these aspects are studied ethnographically, using a combination of participation, interviewing, and recordings of interaction, in Latino homes and social organizations, as well as in Israeli NGOs which advocate for labor migrants vis-a-vis the state. In each case, the effort is to site Latinos' ethnolinguistic emergence in the broader multiplicity of processes of Israeli heteroglossia. The dissertation in essence seeks to describe and help theorize this multiplicity, and the cross-cutting processes of the enregisterment of ethnicity, modernity, and diaspora that are most at play in the constitution of Latinos' sense of themselves as distinct in Israel, as well as in the Israeli public recognition of native Hebrew-speaking "children of foreign workers" as potential citizens.