Drug Interactions Casebook

This remarkable volume of case vignettes was written to complement the principles detailed in the comprehensive work "Concise Guide to Drug Interaction Principles for Medical Practice: Cytochrome P450s, UGTs, P-Glycoproteins," Second Edition, published by American Psychiatric Publishing, Inc. Each case is thoroughly referenced and depicts real clinical events. Many are direct narrations from patients of the author or his colleagues, with identifiers subtly altered to ensure confidentiality. Others are constructed around well-known, accepted, and multiply-verified interactions.

The introductory chapter reviews core concepts and summarizes the P450 system, phase II glucuronidation and P-glycoproteins. Subsequent chapters are organized by the nature of the metabolic processes that account for the depicted drug interactions. At the end of this volume is a revealing self-assessment test case so readers can evaluate their progress in diagnosing drug interactions.

Thoroughly indexed and referenced, with three indispensable appendices of tables for quick reference to the P450 system, UGTs, and P-glycoproteins, the case vignettes in this exceptional work illustrate interactions with both psychoactive agents and drugs from other branches of medicine.

As such, this essential companion to more in-depth analyses of the P450 system will find an immediate audience among not only psychiatrists but also a wide range of medical specialists and generalists, as well as those who are in any way acquainted with the mental health field.