AN INVESTIGATION INTO THE RELAXATION BEHAVIOR OF PHARMACEUTICAL FILM COATINGS.

The effect of the addition of the plasticizers dibutyl phthalate and polyethylene glycol 200 on the primary relaxation behavior of Eudragit S100, an enteric coating, was also evaluated in this dissertation. Creep compliance measurements were performed on films in the glass transition region. Both plasticizers were found to increase the mechanical rate of response of the polymer. A free volume approach was used to describe plasticizing efficiency and it was found that dibutyl phthalate was more effective