Incorporating new information that has become available in recent years, the authors explore hypotheses about the integrated response these systems often have. They explore topics ranging from disturbance of homeostasis, changes in metabolic processes, damage of cellular structures to acquired tolerance, effects on aging processes, and survival and cell death. By analyzing all these aspects in detail at the molecular, biochemical, and physiological level of the cell, the authors give you a thorough look at the relationship between an organism and its environment at the cellular level.