Metaphysics as a philosophical discipline has long been under fire for its doctrinal presumptions, but never more so than under the hegemony of science. Yet, as the essays in this volume demonstrate, it remains an indispensable tool for thinkers in all areas of research in which the human creature is under the spotlight. That this involves a reversal of competences has not been seriously accepted—predominantly in terms of the gulf between autonomous agency and the mechanistic doxa under which science is compelled to operate. This volume seeks to put the torch on these discrepancies, where presuppositions end and understanding must take over.