Minimum Steric Difference

This series of monographs, the result of many years of work by the authors, offers a different approach to the problem of drug action. Starting from a simple concept of the ``hypermolecule,'' (a composite of the molecular structures of a series of compounds), the MTD approach elucidates the detailed relationships between the molecular structure of a drug and its biological activity. Brings together an impressive array of examples to indicate the utility of the described method.