Chiral Auxiliaries and Ligands in Asymmetric Synthesis

"Lessons learned in organic chemistry -- from the tragedy of thalidomide to the challenges of HIV -- provide the backdrop against which this updated translation of the acclaimed Synthèse et Catalyse Asymétrique deals with the efficient synthesis of chiral nonracemic organic compounds in pharmaceutical and medical research. Because chiral molecules come in 'right-' or 'left-handed' forms that do not behave the same toward enzymes and therefore can display different physiological activities, it is crucial that chemists get the form they want when synthesizing these very useful compounds. These issues have led almost simultaneously to stringent marketing regulations and exciting developments in the filed over the past decade, and have spurred this provocative and authoritative book. An in-depth guide for chemists and researchers involved in organic synthesis, and an extremely useful text/self-study for graduate students ..."--Back cover.